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Importantly, PDUFA is not static
At industrial-scale production, the cellular glutathione concentration of Candida utilis and S.cerevisiae strains, the most commonly used microorganisms for commercial glutathione production, is 0.1-1% dry cell weight ( S.bacillaris strains PAS13 (0.012%) and FRI751 (0.008%), and S.cerevisiae EC1118 (0,007%) in this study
Caroline Leaf
Presented for research literature review only Wu J et al
Consistency and follow-up visits help maximize success
Estimand definitions differ across trials
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